Chromium exists in nature as complexes of two stable oxidation states – trivalent chromium(III) and hexavalent chromium(VI). Although trivalent chromium is required in trace amounts for sugar and lipid metabolism in humans and its deficiency may cause a disease called chromium deficiency; hexavalent chromium is toxic and carcinogenic. As chromium compounds were used in dyes and paints and the tanning of leather, these compounds are often found in soil and groundwater at abandoned industrial sites, now needing environmental cleanup and remediation. The Bioinorganic Chemistry of Chromium: From Biochemistry to Environmental Toxicology takes a critical look at what the biochemical data indicate about chromium's role in the body and the biological mechanisms of its toxicology. Topics covered include: What do we know about the biochemical roles and mechanisms of chromium? Is chromium an essential element in the mammalian diet? Is chromium(III) effective as a nutraceutical, a therapeutic agent, and as a supplement in animal feed? What is the biochemistry behind the toxicology of chromium(III) and chromium(VI):the mechanisms of metabolism, genetic and epigenetic effects, and disruption of cell signalling? What are the current chromium(VI) policies and positions from regulatory agencies? The Bioinorganic Chemistry of Chromium: From Biochemistry to Environmental Toxicology is an important contribution to the bioinorganic and trace element biochemical fields which will find a place on the bookshelves of bioinorganic chemists, biochemists, inorganic chemists, toxicologists, nutritionists and regulatory affairs professionals.
Arsenic, antimony and bismuth, three related elements of group 15, are all found in trace quantities in nature and have interesting biological properties and uses. While arsenic is most well known as a poison – and indeed the contamination of groundwater by arsenic is becoming a major health problem in Asia – it also has uses for the treatment of blood cancer and has long been used in traditional chinese medicine. Antimony and bismuth compounds are used in the clinic for the treatment of parasitic and bacterial infections. Biological Chemistry of Arsenic, Antimony and Bismuth is an essential overview of the biological chemistry of these three elements, with contributions from an international panel of experts. Topics covered include: chemistry of As, Sb and Bi biological chemistry of arsenic biological chemistry of Sb and Bi arsenic and antimony speciation in environmental and biological samples arsenic in traditional chinese medicine arsenic in aquifers biomethylation of As, Sb and Bi uptake of metalloids by cells bismuth complexes of porphyrins and their potential in medical applications Helicobacter pylori and bismuth metabolism of arsenic trioxide in blood of the acute promyelocytic leukemia patients anticancer properties of As, Sb and Bi radio-Bi in cancer therapy genotoxicity of As, Sb and Bi metallomics as a new technique for As, Sb and Bi metalloproteomics for As, Sb and Bi Biological Chemistry of Arsenic, Antimony and Bismuth conveys the essential aspects of the bioinorganic chemistry of these three elements, making this book a valuable complement to more general bioinorganic chemistry texts and more specialized topical reviews. It will find a place on the bookshelves of practitioners, researchers and students working in bioinorganic chemistry and medicinal chemistry.
Connecting inorganic chemistry to the hottest topic in materials science, this timely resource collects the contributions made by leading inorganic chemists towards nanomaterials research. The second volume in the “Wiley Encyclopedia of Inorganic Chemistry Methods and Applications Series,” this signature title concentrates on recent developments in the field and includes all key topics such as nanowires, nanotubes, biomineralization, supramolecular materials and much more. This volume is also available as part of Encyclopedia of Inorganic Chemistry, 5 Volume Set. This set combines all volumes published as EIC Books from 2007 to 2010, representing areas of key developments in the field of inorganic chemistry published in the Encyclopedia of Inorganic Chemistry. Find out more.
This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic.
An updated overview of the rapidly developing field of green engineering techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique’s features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry. It is divided into 4 parts. The first part introduces readers to the concepts of green chemistry and green engineering, global environmental regulations, green analytical chemistry, green solvents, and green chemistry metrics. The other three sections cover green catalysis, green synthetic techniques, and green techniques and strategies in the pharmaceutical industry. Includes more than 30% new and updated material—plus seven brand new chapters Edited by highly regarded experts in the field (Berkeley Cue is one of the fathers of Green Chemistry in Pharma) with backgrounds in academia and industry Brings together a team of international authors from academia, industry, government agencies, and consultancies (including John Warner, one of the founders of the field of Green Chemistry) Green Techniques for Organic Synthesis and Medicinal Chemistry, Second Edition is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in organic chemistry and medicinal chemistry.
A comprehensive treatment of the chemistry and physics of mechanical hardness Chemistry and Physics of Mechanical Hardness presents a general introduction to hardness measurement and the connections between hardness and fundamental materials properties. Beginning with an introduction on the importance of hardness in the development of technology, the book systematically covers: Indentation Chemical bonding Plastic deformation Covalent semiconductors Simple metals and alloys Transition metals Intermetallic compounds Ionic crystals Metal-metalloids Oxides Molecular crystals Polymers Glasses Hot hardness Chemical hardness Super-hard materials Chemistry and Physics of Mechanical Hardness is essential reading for materials scientists, mechanical engineers, metallurgists, ceramists, chemists, and physicists who are interested in learning how hardness is related to other properties and to the building blocks of everyday matter.
Discover the science of beer and beer making Ever wondered just how grain and water are transformed into an effervescent, alcoholic beverage? From prehistory to our own time, beer has evoked awe and fascination; it seems to have a life of its own. Whether you're a home brewer, a professional brewer, or just someone who enjoys a beer, The Chemistry of Beer will take you on a fascinating journey, explaining the underlying science and chemistry at every stage of the beer making process. All the science is explained in clear, non-technical language, so you don't need to be a PhD scientist to read this book and develop a greater appreciation for the world's most popular alcoholic drink. The Chemistry of Beer begins with an introduction to the history of beer and beer making. Author Roger Barth, an accomplished home brewer and chemistry professor, then discusses beer ingredients and the brewing process. Next, he explores some core concepts underlying beer making. You'll learn chemistry basics such as atoms, chemical bonding, and chemical reactions. Then you'll explore organic chemistry as well as the chemistry of water and carbohydrates. Armed with a background in chemistry principles, you'll learn about the chemistry of brewing, flavor, and individual beer styles. The book offers several features to help you grasp all the key concepts, including: Hundreds of original photographs and line drawings Chemical structures of key beer compounds Glossary with nearly 1,000 entries Reference tables Questions at the end of each chapter The final chapter discusses brewing at home, including safety issues and some basic recipes you can use to brew your own beer. There's more to The Chemistry of Beer than beer. It's also a fun way to learn about the science behind our technology and environment. This book brings life to chemistry and chemistry to life.
This go-to text provides information and insight into physical inorganic chemistry essential to our understanding of chemical reactions on the molecular level. One of the only books in the field of inorganic physical chemistry with an emphasis on mechanisms, it features contributors at the forefront of research in their particular fields. This essential text discusses the latest developments in a number of topics currently among the most debated and researched in the world of chemistry, related to the future of solar energy, hydrogen energy, biorenewables, catalysis, environment, atmosphere, and human health.
The efficacy of isocyanide reactions in the synthesis of natural or naturallike products has resulted in a renaissance of isocyanide chemistry. Now isocyanides are widely used in different branches of organic, inorganic, coordination, combinatorial and medicinal chemistry. This invaluable reference is the only book to cover the topic in such depth, presenting all aspects of synthetic isonitrile chemistry. The highly experienced and internationally renowned editor has brought together an equally distinguished team of authors who cover multicomponent reactions, isonitriles in total synthesis, isonitriles in polymer chemistry and much more.
The tools you need to ace your Chemisty II course College success for virtually all science, computing, engineering, and premedical majors depends in part on passing chemistry. The skills learned in chemistry courses are applicable to a number of fields, and chemistry courses are essential to students who are studying to become nurses, doctors, pharmacists, clinical technicians, engineers, and many more among the fastest-growing professions. But if you're like a lot of students who are confused by chemistry, it can seem like a daunting task to tackle the subject. That's where Chemistry II For Dummies can help! Here, you'll get plain-English, easy-to-understand explanations of everything you'll encounter in your Chemistry II class. Whether chemistry is your chosen area of study, a degree requirement, or an elective, you'll get the skills and confidence to score high and enhance your understanding of this often-intimidating subject. So what are you waiting for? Presents straightforward information on complex concepts Tracks to a typical Chemistry II course Serves as an excellent supplement to classroom learning Helps you understand difficult subject matter with confidence and ease Packed with approachable information and plenty of practice opportunities, Chemistry II For Dummies is just what you need to make the grade.
Physical Inorganic Chemistry contains the fundamentals of physical inorganic chemistry, including information on reaction types, and treatments of reaction mechanisms. Additionally, the text explores complex reactions and processes in terms of energy, environment, and health. This valuable resource closely examines mechanisms, an under-discussed topic. Divided into two sections, researchers, professors, and students will find the wide range of topics, including the most cutting edge topics in chemistry, like the future of solar energy, catalysis, environmental issues, climate changes atmosphere, and human health, essential to understanding chemistry.
A concise, robust introduction to the various topics covered by the discipline of forensic chemistry The Forensic Chemistry Handbook focuses on topics in each of the major chemistry-related areas of forensic science. With chapter authors that span the forensic chemistry field, this book exposes readers to the state of the art on subjects such as serology (including blood, semen, and saliva), DNA/molecular biology, explosives and ballistics, toxicology, pharmacology, instrumental analysis, arson investigation, and various other types of chemical residue analysis. In addition, the Forensic Chemistry Handbook: Covers forensic chemistry in a clear, concise, and authoritative way Brings together in one volume the key topics in forensics where chemistry plays an important role, such as blood analysis, drug analysis, urine analysis, and DNA analysis Explains how to use analytical instruments to analyze crime scene evidence Contains numerous charts, illustrations, graphs, and tables to give quick access to pertinent information Media focus on high-profile trials like those of Scott Peterson or Kobe Bryant have peaked a growing interest in the fascinating subject of forensic chemistry. For those readers who want to understand the mechanisms of reactions used in laboratories to piece together crime scenes—and to fully grasp the chemistry behind it—this book is a must-have.
It is now possible to enter a chemistry degree course at many UK universities without any formal maths training beyond age 16. Addressing this deficiency requires students to take additional mathematics training when entering university, yet the relevance of maths to chemistry is often poorly appreciated by chemistry students. In addition, many service courses are either too abstract, or aimed at physicists and engineers, for students of chemistry, who are not inclined to study mathematical techniques per se and do not make the connection between the maths they are taught and the chemistry they want to study. Based on the successful at a Glance approach, with integrated double page presentations explaining the mathematics required by undergraduate students of chemistry, set in context by detailed chemical examples, this book will be indispensable to all students of chemistry. By bringing the material together in this way the student is shown how to apply the maths and how it relates to familiar concepts in chemistry. By including problems (with answers) on each presentation, the student is encouraged to practice both the mathematical manipulations and the application to problems in chemistry. More detailed chemical problems at the end of each topic illustrate the range of chemistry to which the maths is relevant and help the student acquire sufficient confidence to apply it when necessary.
What’s it really like to be a chemist? Leading chemists share what they do, how they do it, and why they love it. “Letters to a young …” has been a much-loved way for professionals in a field to convey their enthusiasm and the realities of what they do to the next generation. Now, Letters to a Young Chemist does the same for the chemical sciences. Written with a humorous touch by some of today’s leading chemists, this book presents missives to “Angela,” a fictional undergraduate considering a career in chemistry. The different chapters offer a mix of fundamental principles, contemporary issues, and challenges for the future. Marye Anne Fox, Chancellor of the University of California San Diego, talks about learning to do research and modern physical organic chemistry. Brothers Jonathan and Daniel Sessler explain the chemistry of anesthetics that make modern surgery possible while Elizabeth Nolan talks about biological imaging. Terry Collins talks about green chemistry, a more sustainable way of doing chemistry, while several authors including Carl Wamser, Harry Gray, John Magyar, and Penny Brothers discuss the crucial contributions that chemists can make in meeting global energy needs. Letters to a Young Chemist gives students and professionals alike a unique window into the real world of chemistry. Entertaining, informative, and full of honest and inspiring advice, it serves as a helpful guide throughout your education and career. “The different chapters describe both the wonders of the molecular world and the practical benefits afforded by chemistry … and if any girl out there thinks that chemistry is a man’s world, this book should be a good antidote.” —Marye Anne Fox, Chancellor of the University of California, San Diego, and winner of the 2009 US National Medal of Science “Letters to a Young Chemist offers significant ammunition for motivating young people to consider chemistry as a career. … This book should also be required reading for all faculty members who teach chemistry in high schools, colleges, and universities.” —Stephen J. Lippard, Arthur Amos Noyes Professor of Chemistry, Massachusetts Institute of Technology, and winner of the 2006 US National Medal of Science